Time to Rethink the Unthinkable: Upfront Biopsy of Children With Newly Diasnosed Diffuse Intrinsic Pontine Glioma (DIPG)

In November’s featured publication, Dr. Kieran discusses diffuses intrinsic pontine glioma (DIPG) biopsy.  During the past 50 years, biopsy for these tumors have been discouraged due to excessive toxicity of the procedure.  However, Dana-Farber Cancer Institute and Boston Children’s Hospital have recently opened a multi-site national clinical trial of DIPG biopsy and chemotherapy to change the current dogma and improve treatment outcomes for patients.