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Congratulations Daphne on being elected to the National Academy of Medicine!

Congratulations Daphne on being elected to the National Academy of Medicine!

The DFCI PLGA program congratulations our own Daphne Haas-Kogan, MD on her election to the National Academy of Medicine. This is one of the highest honors in the fields of health and medicine. Daphne is recognized for her research on genetic abnormalities of brain tumors and for successfully translating laboratory discovers to the treatments. Please […]

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PLGA Appreciation Lunch

PLGA Appreciation Lunch

On September 20, we all piled into the patio at Sweet Cheeks in Fenway for a fabulous “Appreciation Lunch” sponsored by the PLGA Fund families. It was a special day: the sun was shining; the food was delicious; and the good cheer flowed. It’s a rare occurrence for all the various members of the PLGA […]

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Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes

Dr. Mike Eck and colleagues have published their tour de force structural study of BRAF in complex with MEK and 14-3-3 dimers. This work explains longstanding questions about the biochemical behavior of BRAF and provides a foundation for understanding BRAF activation by oncogenic mutations as well as pharmacologic inhibition. Please go to: https://www.ncbi.nlm.nih.gov/pubmed/31581174 to read […]

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Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.

In this featured publication, lead authors Zachary Reitman, MD, PhD and Brenton Paolella, PhD, and others with Mimi Bandopadhayay, MBBS, PhD and Rameen Beroukhim, MD, PhD use single cell sequencing technology to examine the cellular state of individual tumor cells. They find that PA cancer cells often look like astrocytes at the RNA level, but […]

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John, Mimi and Amy

John, Mimi and Amy

John Ragnoni, Dr. Mimi Bandopadhayay and Amy Weinstein working hard, but still having fun at a recent PBTF meeting.

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PMC Teams Visit June 12, 2019

PMC Teams Visit June 12, 2019

We had a great time the evening of June 12, 2019 when PMC team members came to visit. Dr. Mimi Bandopadhayay spoke and 6 of our young investigators gave updates on their work. The talks were followed by a check presentation and laboratory tours. The 2018 PMC teams raised $1,746,871.85 for the PLGA program! As […]

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Management of pediatric low-grade glioma.

In this featured publication, investigators review recent results of treatments for pediatric low-grade gliomas, including standard chemotherapy, therapies targeting the mitogen-activated protein kinase (MAPK) pathway, and proton-beam radiation therapy.

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Welcome Bill, Kimberly and John!

Bill Tiller, CEO of The Pediatric Brain Tumor Foundation (PBTF), Kimberly Roy-Canning, PBTF Northeast Regional Director, and John D’Ambrosio, PBTF Northeast Regional Campaign Manager came for a visit to DFCI on Tuesday, April 9, 2019. It was a lovely evening of presentations by the Dana-Farber PLGA program scientists, tours of the Jimmy Fund Clinic and […]

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Team Nathan PMC Riders – Lab Visit and Check Presentation

Team Nathan PMC Riders – Lab Visit and Check Presentation

Team Nathan raised $157,967 riding in the 2018 PMC. They came for a lab visit and check presentation on Feb 13. It was a special evening and awesome opportunity for us to show what we do in the lab.  Two teams, riders and scientists, together are a formidable force in the fight against PLGA!

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Dana-Farber helps “Flip the Switch” with the Pediatric Brain Tumor Foundation

Dana-Farber helps “Flip the Switch” with the Pediatric Brain Tumor Foundation

Dana-Farber’s Susan Chi, MD, Jill MacDonald, RN, BSN, CPON, Mimi Bandopadhayay, PhD, MBBS, and Larisa Condurat, PhD help the Pediatric Brain Tumor Foundation “Flip the Switch” on December 27th to light up the Prudential Center in support of pediatric brain tumor research.

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